Profile: greenovation Biotech GmbH is a service provider and supplier for the pharmaceutical and biotech industry. We have technologies for production and refinement of complex pharmaceutical proteins in moss cells. Bryo-Master™ system is implemented for the production of therapeutic proteins in stable moss cell lines. At the beginning, moss protonema is cultivated in photobioreactors. The moss tissue is harvested and treated with special enzymes, which digest the cell wall of the moss plants. Moss cells without cell wall emanate from this process. Next, the moss protoplasts are transfected with DNA (red) coding for the desired product. The DNA is stably integrated into the genome of the moss cell. After regeneration of the cell wall best producer cell lines are identified among the modified moss plants. Next, the selected moss plants are cultivated in photobioreactors. The moss protonema is producing the desired product in a sustainable manner and the therapeutic proteins are secreted into the medium. The products are already existent in the bioreactor before the downstream process. Bryo-Speed™ system is fast for making of glycoproteins through moss protoplasts.
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• | Biopharmaceutical Drugs |