By baculovirus, is meant any baculovirus of the family Baculoviridae, such as a nuclear polyhedrosis virus (NPV). Baculoviruses are a large group of evolutionarily related viruses, which infect only arthropods, indeed, some baculoviruses only infect insects that are pests of commercially important agricultural & forestry crops, while others are known, that specifically infect other insect pests. Since baculoviruses infect only arthropods, they pose little or no risk to humans or the environment. Baculoviruses may be occluded or non-occluded. The nuclear polyhedrosis viruses (NPV) are one baculovirus subgroup, which are occluded. That is, a characteristic feature of the NPV group is that many virions are embedded in a crystalline protein matrix referred to as an occlusion body. Examples of NPVs include Lymantria dispar NPV (gypsy moth NPV), Autographa californica MNPV, Anagrapha falcifera NPV (celery looper NPV), Spodoptera litturalis NPV, Spodoptera frugiperda NPV, Heliothis armigera NPV, Mamestra brassicae NPV, Choristoneura fumiferana NPV, Trichoplusia ni NPV, Heliocoverpa zea NPV and Rachiplusia ou NPV. For field use occluded viruses are preferable due to their greater stability since the viral polyhedrin coat provides protection for the enclosed infectious nucleocapsids. Littovir is a nucleopolyhedrosis virus (NPV) product introduced by Andermatt Biocontrol for the control of the Egyptian cotton leafworm (Spodoptera littoralis), one of the most serious pests worldwide & a particular problem in cotton, vegetables & cereals. Littovir is the sixth baculovirus product produced and distributed worldwide by Andermatt Biocontrol.