Profile: MoBiTec GmbH provides tools for molecular & cell biology. Our bacillus megaterium expression system provides a tool for stable and high-yield protein production. Our bacillus megaterium has proven to be an alternative host to Escherichia coli for heterologous gene expression. Unlike other bacilli strains, proteolytic degradation by alkaline proteases is avoided. In addition, there are no endotoxins found in the cell wall. We provide a wide range of useful vectors for this system that are adaptable to most applications and protein purification methods. Our nuclean silica matrix DNA purification is a quick and efficient system for the purification of single & double-stranded DNA from solutions and agarose gels. The method is based on the high affinity of nucleic acids to the large surface of the silica particles in the presence of a chaotropic salt. After two washing steps, the purified DNA can be eluted quantitatively in a small volume of water or TE buffer. No further purification is required for subsequent enzymatic procedures.