Profile: M-Scan Inc. is a chemical analysis laboratory specializing in chemical testing as well as high-end GLP/GMP contract analytical services, consultancy & training based on mass spectrometry and chromatography. We provide analytical services in the area of life sciences, including protein analysis, pharmaceutical analysis and bioanalysis to support the drug development program. We offer a comprehensive portfolio of environmental testing, oil finger printing, chemical analysis and forensic analytical testing services. Amino acid analysis is used in protein characterization to analyze peptide or protein concentration, content & molar ratio or, alongside UV spectrophotometry, to gain an extinction coefficient. This analysis is used throughout all stages of drug discovery, or to demonstrate comparability and consistency between batches for release during the manufacturing phase. Glycosylation site analysis is used to determine the population profile of the N-glycans or O-glycans present at each glycosylation site in a glycoprotein. This information can be used in all stages of drug development in conjunction with linkage analysis to provide a detailed picture of the glycans present. It can also be used to demonstrate consistency between batches for release during the manufacturing process. High pressure liquid chromatography (HPLC) is a liquid chromatographic technique in which the sample is forced through the column under high pressure. In normal phase (NP-HPLC), the mobile phase is non-polar and the stationary phase is polar. In reverse-phase (RP-HPLC), the polarity of the stationary and mobile phases is reversed, allowing only hydrophobic interactions with the analytes.