Profile: IQ Products supplies a range of products for perinatal diagnostics, transplantation related diagnostics and routine flow cytometry. During the early stages of apoptosis, phosphatidylserine (PS) becomes exposed on the outside of the cell membrane. This can be specifically detected by PS binding proteins, such as, Annexine V. Our product annexin V possesses anticoagulant properties & is proven to be a useful tool in detecting apoptotic cells since it preferentially binds to negatively charged phospholipids like PS in the presence of calcium & shows minimal binding to phosphatidylcholine and sphingomyeline. Changes in PS asymmetry, analyzed by measuring Annexin V binding to the cell membrane, can be detected prior to morphological changes associated with apoptosis and loss of membrane integrity.