Profile: Genewiz, Inc. is a contract research organization specializing in DNA sequencing, molecular biology, and genomic services. We offer transgenic mouse genotyping services. This service includes PCR-based genotyping assay design, optimization & validation of the genotyping assay, extraction of genomic DNA from biopsy tissues, PCR amplification of genomic DNA samples, and electrophoresis & genotype identification. We can also perform a genotyping assay according to the preferred protocol. We provide custom hybridoma development services to meet the monoclonal antibody needs efficiently, effectively and economically. This service includes immunization of mice & serum screening, hybridoma fusion, cloning of hybridoma colonies, screening of hybridoma supernatants, and expansion of positive clones. We provide GLP (Good Laboratory Practice) DNA sequencing and plasmid preparation services to various pharmaceutical, biopharmaceutical, biotechnology & clinical institutions for regulatory submissions & applications that must meet regulatory requirements. We render DNA sequencing including double strand sequence confirmation, primer walking sequencing, nucleic acid extraction, reverse transcription PCR & sequencing, PCR amplification & sequencing, and plasmid DNA preparation. All our GLP DNA sequencing services provide double-strand and a minimum of four-fold coverage of sequences of interest. Our GLP plasmid DNA preparation services can accommodate requests for various amounts of plasmid DNA. Final products are tested with one or more customized quality control assays to ensure integrity and accuracy.