Profile: ChinaPeptides Co., Ltd. is mainly involved in peptide synthesis industry. Our process includes both automatic and manual peptide synthesizers, purification, and analytical HPLC systems. The first stage of the solid phase peptide synthesis (SPPS) consists of peptide chain assembly with protected amino acid derivatives on a polymeric support. The second stage of the technique is the cleavage of the peptide from the resin support with the concurrent cleavage of all side chain protecting groups to give the crude free peptide. The general principle of SPPS is one of repeated cycles of coupling-deprotection. The free N-terminal amine of a solid-phase attached peptide is coupled to a single N-protected amino acid unit. This unit is then de-protected, revealing a new N-terminal amine to which a further amino acid may be attached. There are two major used forms of solid phase peptide synthesis. They are Fmoc (base labile alpha-amino protecting group) and t-Boc (acid labile protecting group). Each method involves different resins and amino acid side-chain protection and consequent cleavage/de-protection steps. Fmoc chemistry is known for generating peptides of higher quality and in greater yield than t-Boc chemistry.