Chemometrics is the application of statistics to the analysis of chemical data (from organic, analytical or medicinal chemistry) and design of chemical experiments & simulations. Chemometrics is an approach to analytical chemistry based on the idea of indirect observation. Measurements related to the chemical composition of a substance are taken, and the value of a property of interest is inferred from them through some mathematical relation. Basically, chemometrics is a process. Measurements are made, data is collected, and information is obtained to periodically assess & acquire knowledge. This, in turn, has led to a new approach for solving methodical problems: (1) measure a phenomenon or process using chemical instrumentation that generates data inexpensively, (2) analyze the multivariate data, (3) iterate if necessary, (4) create & test the model, and (5) develop fundamental multivariate understanding of the process. Chemoinformatics is a subfield of chemometrics, which encompasses the analysis, visualization, and for use of chemical structural information as a surrogate variable evidently has this term been coined. Chemometrics techniques are applied to characterize and differentiate diverse microbial species & strains using Fourier transform infrared spectroscopy.