Research in the Chemical Engineering focuses on manipulation of cells, DNA, and proteins for applications in biotechnology & clinical medicine. Both theoretical and experimental tools are developed to address current scientific & engineering issues of high societal impact. Current efforts of bioengineering research are in the areas of genomics and metabolic engineering, bioinformatics, biosensors, biomimetic systems, blood flow regulation & artificial blood substitutes. Cutting edge technology, such as DNA microarray and nano fabrication technology are being used in conjunction with mathematical tools to advance bioscience & engineering. Significant progress includes the development of an artificial gene circuit for production of a novel product in E. coli, a hierarchical model for a DNA microarray, discovery of a novel thermostable, chiral-specific enzyme for L-amino acid synthesis, construction of a novel metabolic pathway in E. coli that synthesizes a large variety of important bioactive molecules & discovery of a novel mechanism that regulates blood flow.