Profile: Centocor, Inc. focuses on treating cancer and immune-mediated inflammatory disorders such as rheumatoid arthritis and plaque psoriasis. We are specialized in monoclonal antibody technology, a cutting-edge approach that launched a new generation of products to treat immune-related diseases. Our products are used to treat ulcerative colitis, Crohn's disease, ankylosing spondylitis, plaque psoriasis, psoriatic arthritis, and rheumatoid arthritis. Remicade® is indicated for reducing symptoms of active arthritis, inhibiting the progression of structural damage, and improving physical function in patients with psoriatic arthritis. This product is also indicated for reducing the number of draining enterocutaneous & rectovaginal fistulas and maintaining fistula closure in adult patients with fistulizing Crohn's disease. Remicade® used in combination with methotrexate, can reduce signs & symptoms, help stop further joint damage, and improve physical function in many patients with moderate to severe rheumatoid arthritis.