Profile: Calypte Biomedical Corporation develops in vitro testing products to improve the diagnosis of Human Immunodeficiency Virus (HIV) infection, sexually transmitted diseases and other chronic diseases. We provide aware™ HIV-1/2 OMT which is a single-use, qualitative, visually read, in vitro immunoassay for the detection of antibodies to HIV Type 1 and Type 2 in human oral fluid specimens. The test is intended for use as a point-of-care aid in the clinical diagnosis of HIV infection. It can be used as a component of a multi-test rapid algorithm in conjunction with other approved HIV-antibody assays.