The distribution and sharing of data & methods is essential not only for distributing the computational demands implied by the large databases, but also to cater to effective interaction between members of multidisciplinary teams. Networking can be performed locally (by LANs) and on a wide scale (Internet). Software engineering skills are needed to build systems & software packages that can be used by scientists, and designing effective user interfaces for these requires human-computer interaction principles to be applied. Web technologies are often used to make bioinformatics data sets and tools available to the scientific community. Many other areas of IT are also used in bioinformatics. Advances in internet technology have largely affected the bioinformatics resources as heterogeneous sources of information. It facilitates the uniform access to the educational, academic & research information sources to bioinformaticians for their research & developmental activities. Access to sequence data is critical, and much of the new sequence data are distributed over the internet. Currently there are at least 400 internet-accessible databases of biological data. The internet also provides a means to distribute software and enables researchers to perform sophisticated analyses on remote servers.