Profile: BioPur AG manufactures highly purified proteins and enzymes derived from human & animal sources for research use. Our focus is on the extraction of proteins and enzymes from native plasma & other sources. We also offer customized purification of very rare proteins in larger quantities. Our product line includes coagulation factors like thrombin as well as extra-cellular-martix (ECM) proteins for cell-culture-research like fibronectin and laminin. We have a wide range of different customers from academic and government research institutions, biotechnology & pharmaceutical companies, to hospitals and reference laboratories. Albumin, a soluble monomeric protein, comprises about half of serum proteins. It is a carrier for steroids, fatty acids, and thyroid hormones & stabilizes extracellular fluid volume. It is a globular unglycosylated serum protein and is synthesized in the liver as preproalbumin. Serum albumins are important in regulating blood volume by maintaining the oncotic pressure of the blood compartment. They also serve as carriers for molecules of low water solubility. They isolate their hydrophobic nature, including lipid soluble hormones, bile salts, unconjugated bilirubin, free fatty acids (apoprotein), calcium, ions (transferrin), and some drugs like warfarin, phenobutazone, clofibrate & phenytoin. Cholinesterase is an enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. The extracellular matrix (ECM) is a complex structural entity that surrounds and supports the cells within living systems. In mammalian tissues, the ECM is most commonly found in connective tissues such as tendon, cartilage, bone or dermis of the skin. The ECM is produced and maintained by the cells that inhabit it. The proteins within the ECM can be divided into several classes based upon their structure and function within the ECM.