Profile: Allozyne, Inc. is a protein optimization company that develops improved biological therapeutics to treat multiple areas of medical need. We focus on methods to incorporate amino acid analogs at specific sites into proteins using fermentation based manufacturing, and these amino acid analogs possess unique chemical functions that provide proteins with novel properties not found in nature. We also focus on three general categories of proteins that are manufactured in bacterial fermentation, including cytokines such as IFN beta, single chain antibody fragments, and fusion proteins of high potency small peptide mediators.