Profile: Adooq BioScience is a supplier of biochemicals. We are engaged in manufacturing and supplying small molecule inhibitors including kinase inhibitors on signal pathways such as PI3K, AKT, HDAC, and MARP. VX-765 is a novel Caspase-1 inhibitor, which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18. Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells. Tetrandrine has anti-inflammatory & anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis. SB-505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5), ALK4, and ALK7. Astragaloside A is a novel regulator of HIF-1α and angiogenesis, through the PI3K/Akt pathway in HUVECs that are exposed to hypoxia.