Profile: Acambis Inc. is a vaccine company developing novel vaccines that address significant unmet medical needs. Our ACAM2000® vaccine is a live, vaccinia virus smallpox vaccine for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection. Our ChimeriVax-JE is a live, attenuated, injectable vaccine that provides a convenient single-dose vaccine to travelers and those living in endemic regions. Our Acam-Flu-A™ is a recombinant vaccine that uses a Hepatitis B core protein to deliver M2e, the extracellular domain of the ion channel protein M2.